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Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. In vitro, increases NO2-dependent relaxation of human corpus cavernosum.
Description
Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. In vitro, increases NO2-dependent relaxation of human corpus cavernosum.